Genetic Variation in FADS1 Has Little Effect on the Association between Dietary PUFA Intake and Cardiovascular Disease

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Genetic Variation in FADS1 Has Little Effect on the Association between Dietary PUFA Intake and Cardiovascular Disease123

The unclear link between intake of polyunsaturated fatty acids (PUFAs) and risk of cardiovascular disease (CVD) could depend on genetic differences between individuals. Minor alleles of single-nucleotide polymorphisms (SNPs) in the ∆5 fatty acid desaturase (FADS) 1 gene were associated with lower blood concentrations of long-chain ω-3 (n-3) and ω-6 (n-6) PUFAs, indicating an associated loss of ...

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ژورنال

عنوان ژورنال: The Journal of Nutrition

سال: 2014

ISSN: 0022-3166,1541-6100

DOI: 10.3945/jn.114.192708